Kuwanikwa uye kuwanda kweOmi Keron mutant strains

1. Kuwanikwa uye kuwanda kweOmi Keron mutant strains Musi wa9 Mbudzi, 2021, South Africa yakaona musiyano weB.1.1.529 wekoronavirus itsva kubva mumuenzaniso kekutanga. Mumavhiki maviri chete, iyo mutant dhizaini yakave yakagwinya inochinja-chinja yenyaya nyowani yehutachiona hwekorona muGauteng Province, South Africa, uye kukura kwayo kwakakurumidza. Musi waMbudzi 26, WHO yakaitsanangura sechishanu "mutsauko wekunetsekana" (VOC), yakatumidza zita rechiGiriki Omicron (Omicron) musiyano. Kubva muna Mbudzi 28, South Africa, Israel, Belgium, Italy, United Kingdom, Austria, neHong Kong, China, vakaongorora mapindiro emutant strain. Iko kupinza kweiyo mutant strain haisati yawanikwa mune mamwe matunhu nemaguta munyika yangu. Omi Keron mutant yakatanga kuwanikwa uye yakashumwa kuSouth Africa, asi hazvireve kuti hutachiona hwakavapo muSouth Africa. Nzvimbo iyo mutant yakawanikwa haisati iri iyo nzvimbo yakabva.

2. Zvikonzero zvinogona kuitika zvekubuda kweOmi Keron mutants Maererano neruzivo rwazvino rwakagoverwa nedatabase nyowani yehutachiona hweGISAID, huwandu hwenzvimbo dzekuchinja kwehutachiona hwekorona itsva Omi Keron mutant strain yakanyanya kudarika iyo yehutachiona hwekorona hutsva. mutant strains anga achitenderera mumakore maviri apfuura, kunyanya muhutachiona spike (Spike) protein mutations. . Zvinofungidzirwa kuti zvikonzero zvekubuda kwayo zvinogona kunge zviri zvitatu zvinotevera: (1) Mushure mekunge murwere we immunodeficiency abatwa nekoronavirus itsva, akawana nguva yakareba yekushanduka-shanduka mumuviri kuunganidza nhamba huru yekuchinja, iyo zvinoparadzirwa netsaona; (2) imwe hutachiona hweboka remhuka New coronavirus, hutachiona hunoita shanduko inoshanduka panguva yekupararira kwehuwandu hwemhuka, uye chiyero chekuchinja chakakwira kupfuura chevanhu, chobva chapinda muvanhu; (3) Iyi mutant dhizaini yakaramba ichitenderera kwenguva yakareba munyika kana matunhu uko kutariswa kwekuchinja kweiyo coronavirus genome kuri kushomeka. , Nekuda kwekusakwana kwekutarisa kugona, mavhairasi echizvarwa chepakati ekushanduka kwawo haagone kuonekwa nenguva.

3. Kugona kutapurirana kweOmi Keron mutant strain Parizvino, hapana data yakarongeka yekutsvagisa pamusoro pekutapurirana, pathogenicity, uye kugona kupukunyuka kwekudzivirira kweOmi Keron mutants munyika. Nekudaro, iyo Omi Keron musiyano ine zvakare yakakosha amino acid mutation nzvimbo mune ina yekutanga VOC akasiyana Alpha, Beta, Gamma uye Delta spike mapuroteni, anosanganisira akakwidziridzwa cell receptors. Mutation nzvimbo dze somatic affinity uye hutachiona kudzokorora kugona. Epidemiological and laboratory monitoring data inoratidza kuti huwandu hwenyaya dzeOmi Keron variants muSouth Africa hwawedzera zvakanyanya, uye hwave kutsiva mhando dzeDelta (Delta). Iyo yekutapurirana simba inoda kutariswa zvakare uye kudzidzwa.

4. Kukanganisa kweOmi Keron variant strain pamajekiseni nemishonga yekurwisa masoja Zvidzidzo zvakaratidza kuti kuvepo kweK417N, E484A, kana N501Y kuchinja muprotein yeS yekoronavirus itsva kunoratidza kugona kupukunyuka kwe immune; nepo Omi Keron mutant zvakare ine katatu mutation ye "K417N+E484A+N501Y"; uyezve, iyo Omi Keron mutant zvakare Kune akawanda mamwe machinjiro anogona kuderedza kuita neutralizing basa remamwe masoja ekudzivirira chirwere. Iyo yepamusoro-soro yekuchinja inogona kuderedza kushanda kwekudzivirira kweimwe antibody mishonga kurwisa Omi Keron mutants, uye kugona kwemajekiseni aripo kutiza kusadzivirirwa kunoda kutariswa nekutsvagisa.

5. Ko iyo Omi Keron musiyano inokanganisa nucleic acid yekuona reagents parizvino iri kushandiswa munyika yangu? Ongororo ye genome yeOmi Keron mutant strain yakaratidza kuti saiti yayo yekuchinja haikanganisi kunzwisiswa uye kujeka kweiyo mainin nucleic acid yekuona reagents munyika yangu. Nzvimbo dzekuchinja dzeOmi Keron mutant strain dzinonyanya kutariswa munzvimbo inosiyana-siyana yeS protein gene, uye haisi kuwanikwa mune nucleic acid yekuona reagent primers uye probe nzvimbo dzakanangwa dzakaburitswa muchikamu chechisere chenyika yangu "New Coronavirus Pneumonia. Kudzivirira uye Kudzora Chirongwa” (China Iyo ORF1ab gene neN gene yakaburitswa neCenters for Disease Control and Prevention to the world). Zvakadaro, data kubva kumarabhoritari akawanda muSouth Africa inoratidza kuti nucleic acid inoona reagents inoona S gene inogona kusakwanisa kunyatsoona S gene yeOmi Keron musiyano.

6. Matanho akatorwa nenyika nematunhu akakodzera Tichitarisa kukurumidza kuitika kwechirwere cheOmi Keron mutants muSouth Africa, nyika zhinji nematunhu, kusanganisira United States, United Kingdom, European Union, Russia, Israel, Taiwan yenyika yangu uye Hong Kong, vakarambidza kupinda kwevafambi vanobva kumaodzanyemba kweAfrica.

7. Mapinduriro enyika yangu anoyera Dziviriro nekudzora nzira yenyika yedu ye "kudzivirira kwekunze, kudzivirira kwemukati kurwisa rebound" ichiri kushanda kurwisa Omi Keron mutant. Institute of Viral Diseases yeChinese Center for Disease Control and Prevention yakagadzira nzira yekuona nucleic acid yeOmi Keron mutant strain, uye inoenderera mberi nekuita hutachiona hwejenome yekuongorora nyaya dzinogona kutengwa kunze kwenyika. Matanho ataurwa pamusoro achagonesa kuonekwa nenguva kweOmi Keron mutants inogona kutengeswa kunze kwenyika munyika yangu.

8. Kurudziro yeWHO pamhinduro kune Omi Keron mutant strains WHO inokurudzira kuti nyika dzisimbise kuongororwa, kushuma uye tsvakiridzo yekoronavirus itsva, uye kutora matanho anoshanda ehutano kumisa kupararira kwehutachiona; Matanho anobudirira ekudzivirira kutapurira anokurudzirwa kuvanhu anosanganisira kuchengeta chinhambwe chingangoita mita imwe chete munzvimbo dzine veruzhinji, kupfeka masiki, kuvhura mahwindo ekupinza mhepo, uye kuchengeta Geza maoko ako, kukosora kana kuhotsira mugokora kana matishu, kubaiwa nhomba, nezvimwewo, uye dzivisa kuenda kunzvimbo dzisina mweya wekufema zvakanaka kana kuti dzine vanhu vakawanda. Kuenzaniswa nemamwe maVOC akasiyana, hazvisati zvanyatso zivikanwa kana iyo Omi Keron musiyano ine yakasimba kutapurirana, pathogenicity uye immune yekupukunyuka kugona. Tsvagiridzo yakakodzera ichawana yekutanga mibairo mumavhiki mashoma anotevera. Asi izvo zvinozivikanwa parizvino ndezvekuti ese mutant strains anogona kukonzera kurwara kwakanyanya kana kufa, saka kudzivirira kupararira kwehutachiona ndiyo nguva dzose kiyi, uye mushonga wekorona mutsva uchiri kushanda mukuderedza kurwara kwakanyanya nerufu.

9. Pamberi pemusiyano uchangobva kubuda wekoronavirus itsva Omi Keron, chii chinofanira kutariswa neveruzhinji mubasa ravo rezuva nezuva nebasa? (1) Kupfeka mask ichiri nzira inoshanda yekuvhara kupararira kwehutachiona, uye inoshandawo kune Omi Keron mutant strains. Kunyangwe iyo nzira yese yekudzivirira uye yekudzivirira yebooster yapera, zvinodikanwa zvakare kupfeka mask munzvimbo dzemukati dzeveruzhinji, zvifambiso zveveruzhinji nedzimwe nzvimbo. Mukuwedzera, geza maoko ako nguva nenguva uye shandisa ventilate mumba. (2) Ita basa rakanaka rekutarisa hutano hwako. Kana paine zviratidzo zvekufungidzirwa kutsva kwemabayo ecoronary, senge fivha, kukosora, kutadza kufema uye zvimwe zviratidzo, tarisa tembiricha yemuviri nekukurumidza uye tora danho rekunoona chiremba. (3) Deredza kupinda nekubuda zvisina basa. Mumazuva mashoma, nyika zhinji nematunhu zvakatevedzana kuburitsa kunze kweOmi Keron mutant strains. China zvakare yakatarisana nenjodzi yekupinza iyi mutant dhiriji, uye ruzivo rwepasi rose rweiyi mutant strain ichiri shoma. Naizvozvo, kufamba kuenda kunzvimbo dzine njodzi kunofanirwa kudzikiswa, uye kuchengetedzwa kwemunhu panguva yekufamba kunofanirwa kusimbiswa kudzikisa mukana wekutapukirwa neOmi Keron mutant strains.


Nguva yekutumira: Zvita-17-2021